Stegmaier Lab - Identification of new protein targets and small-molecule modulators of malignancy
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​Highlights of our recent work.

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Lu, Diana Y et al. “The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma.” Nature cell biology vol. 25,2 (2023): 285-297. doi:10.1038/s41556-022-01059-8

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Malone, Clare F et al. “The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma.” Science advances vol. 10,22 (2024): eadm9449. doi:10.1126/sciadv.adm9449


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​​Schneider, Constanze et al. “Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia.” Cancer research vol. 84,20 (2024): 
                                          3354-3370.
                           doi:10.1158/0008-5472.CAN-23-3560

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   Lin, Shan et al. “An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML.” Cancer discovery vol. 12,2 (2022): 432-449.
doi:10.1158/2159-8290.CD-20-1851

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