RESEARCH HIGHLIGHTS

The ETS transcription factor ETV6 constrains the transcriptional activity of EWS-FLI to promote Ewing sarcoma
Lu, Diana Y., et al. Nature Cell Biology. 
2023. PMID: 36658220 
DOI: 10.1038/s41556-022-01059-8
Lu-et-al_2023.pdf
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The KAT module of the SAGA complex maintains the oncogenic gene expression program in MYCN-amplified neuroblastoma
Malone, Clare F., et al. Science Advances. 2024. PMID: 38820154 
DOI: 10.1126/sciadv.adm9449
Malone-et-al-2024.pdf
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Targeting the Sodium-Potassium Pump as a Therapeutic Strategy in Acute Myeloid Leukemia
Schneider, Constanze, et al. Cancer Research. 2024. PMID: 39024560 DOI: 10.1158/0008-5472.CAN-23-3560
Schneider-et-al-2024.pdf
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An In Vivo CRISPR Screening Platform for Prioritizing Therapeutic Targets in AML
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Lin, Shan, et al. Cancer Discovery. 2022. PMID: 34531254
DOI: 10.1158/2159-8290.CD-20-1851
Lin-et-al-2022.pdf
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A first-generation pediatric cancer dependency map
Dharia, Neekesh V., et al. Nature Genetics. 2021. PMID: 33753930
DOI: 10.1038/s41588-021-00819-w